MOG Antibody Disease Fact Sheet
for Educators

February 25, 2019


advocating for those with adem, afm, MOGAD, nmosd, on and tm

supporting and advocating for those impacted by MOGAD

What is MOG Antibody Disease?

  • MOG Antibody Disease (MOGAD) is a rare neuro-inflammatory condition that typically causes inflammation in the optic nerve.
  • It can also cause inflammation in the spinal cord, brain, and brain stem.
  • While its cause is unknown, the disease is not transmittable.
  • There is no cure, but treatments are available to prevent inflammatory attacks and to manage symptoms.


  • Loss or blurring of vision in one or both eyes
  • Loss of color vision
  • Paralysis or weakness of a limb or limbs
  • Loss of sensation
  • Loss of bladder or bowel control
  • Fatigue related to the student’s diagnosis or medications, unrelated to the amount of sleep the student gets
  • Seizures


  • Short-term treatments to reduce inflammation during an acute inflammatory attack include IV or oral steroids, plasma exchange (PLEX), and intravenous Immunoglobulin (IVIG).
  • Students diagnosed with MOGAD may be on long-term treatments with medications that suppress the immune system such as mycophenolate mofetil (Cellcept), rituximab (Rituxan), azathioprine (Imuran), low-dose steroids, or IVIG.

Classroom Accommodations

  • Some treatments carry an increased risk of infection to the student with MOGAD, so it is important to keep the classroom clean and sanitized.
  • Good hygiene and hand washing are important.
  • Alert parents/guardians to any illnesses in the classroom (e.g., flu, strep throat, stomach virus).
  • Provide accommodations, required by law, for students who use wheelchairs or other mobility and assistive devices.
  • An emergency plan should be in place for exiting the building, medical emergencies, and a seizure plan (when appropriate).

Learning Considerations

  • Student may need plans in place to assist with learning challenges (e.g. 504, IEP, EHC).
  • Be cognizant of potential visual issues and their impact on learning.
  • Multiple absences are common due to doctor’s appointments, multi-hour infusions, MRIs, etc.
  • Inform parents/guardians of any changes in behavior (e.g., anger outbursts, anxiety, crying, student acting withdrawn) or new learning challenges.
  • Student may be struggling with their diagnosis and the changes MOGAD has caused in their life.
  • Consult with student’s parents/guardians regarding privacy preferences around their condition.

Additional Resources

The Siegel Rare Neuroimmune Association

The MOG Project

For more information on MOGAD, please visit: